Advances in the metabolomic signatures in bone osteoporosis and cancer
Metabolomics in Bone Osteoporosis
DOI:
https://doi.org/10.51607/22331360.2022.71.3.301Keywords:
Biomarkers, bone mineral density, metabolomics, osteoporosis, taurineAbstract
Metabolomic technologies have evolved rapidly contributing the basic metabolic activity of bone diseases. The identification of the metabolic determinant of osteoporosis and bone mass disorder is not yet summarized. Metabolic signalling activity of bone tissue regeneration is crucial for mesenchymal cell differentiation, scaffolds, bone remodelling and metabolism. Numerous of discovered metabolites merit functional follow-up studies to elucidate their role of bone metabolism. The knowledge gained from metabolome investigations is helping to redefine bone disease, find new medication targets for skeletal disorders, and identify biomarkers that are predictive of bone disease. Based on their safety, effectiveness, and cost performance, researchers are becoming more and more interested in creating novel treatments for osteoporosis employing mesenchymal stem cells-based metabolites therapy. The personalized management of osteoporosis-based metabolomics profiling may benefit from advancements in both diagnostic and therapeutic approaches.
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Copyright (c) 2022 Raja Ganesan, Vasantha-Srinivasan Prabhakaran, Arumugam Balasubramanian
This work is licensed under a Creative Commons Attribution 4.0 International License.