Histopathological and Hematological Changes Caused by Head Abscess in Rat

Abstract

A rat with the mass located on the right lateral aspect of the head in the regio infraorbitalis, maxillaris, lateralis nasi dextra, et regio dorsalis nasi was presented for necropsy. Clinically, a severe form of dyspnea and occasional intermittent stridor were observed. Gross examination and histopathology revealed an abscess on the rat’s head. Hematological examination showed macrocytic regenerative hypochromic anemia. In addition, in blood smears stained with May Grunwald Giemsa, numerous spherocytes and anulocytes as well as reticulocytes indicating anemia were observed. Morphological changes found in the lymphocyte (1,1%) and neutrophil cytoplasm (20%) were most probably the result of adverse, toxic effects of various products of purulent inflammation in the head abscess.